Season 16 episodes2008-09-02

Season 16

David Letterman uses mature humor to appeal to his audience in this weeknight series, which gets its music from a house band led by Paul Shaffer. Among the show's most-famous segments are the Top Ten List and Stupid Pet Tricks, the latter of which subsequently led to an additional recurring segment called Stupid Human Tricks.

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Episodes

Season 16

Episode 1

Nicolas Cage, Anna Torv, Terrence Howard

Runtime unavailable

Episode 2

Dr. Phil McGraw, Tilda Swinton, Tricky

Runtime unavailable

Episode 3

Robin Williams, Shannen Doherty, Duffy

Runtime unavailable

Episode 4

John Malkovich, Hayden Panettiere, Steve Earle

Runtime unavailable

Episode 5

Keira Knightley, Thomas L. Friedman

Runtime unavailable

Season 16

Season 16

Nicolas Cage, Anna Torv, Terrence Howard

Dr. Phil McGraw, Tilda Swinton, Tricky

Robin Williams, Shannen Doherty, Duffy

John Malkovich, Hayden Panettiere, Steve Earle

Keira Knightley, Thomas L. Friedman

Jada Pinkett Smith, Chris Russo, Michael Buble

Sen. Barack Obama, LeBron James

Jessica Simpson, Jack Hanna

Meg Ryan, Ricky Gervais

Bill Clinton, Chris Rock

Julianne Moore, Tom Dreesen & Tim Reid, Kings of Leon

Keith Olbermann, Chandra Wilson, Delta Goodrem

Paris Hilton, Usain Bolt, Morningwood

Lance Armstrong, Kristen Wiig, TV on the Radio

Julia Louis-Dreyfus, Michael Cera, Pete Seeger

Anne Hathaway, Josette Sheeran, The Virgins

Kate Walsh, Barry Sonnenfeld, Darius Rucker

Calista Flockhart, Bill Hader, Lucinda Williams

Brian Williams, Tim Robbins

Russell Crowe, Sarah Vowell, The Pretenders

Debra Messing, John Carter, Tegan & Sara

Dennis Quaid, Sarah Chalke, Buddy Guy

Bill Murray, Beck

Jeremy Piven, Elizabeth Banks, Lou Reed

Sarah Silverman, the Teutuls, Ra Ra Riot

Josh Brolin, Amy Sedaris, Blues Traveler

Martin Short, Marv Albert

Sen. John McCain, Ne-Yo

Tina Fey, Frank Caliendo, Tim Montana

Bill O'Reilly, Lauren Conrad

Regis Philbin, James Taylor

Alec Baldwin, Paul Mooney, Ryan Adams

Ashley Olsen, Paul Rudd, John Legend

Marcia Cross, Alan Zweibel

Paris Hilton, Elvis Costello, Jenny Lewis, a Top Ten List by Ricky Gervais

Tom Brokaw, Vera Farmiga

Ben Stiller, Q-Tip

Natalie Portman, Artie Lange, Brad Paisley

Ted Turner, Jamie Oliver, Taylor Swift

Don Rickles, Amy Brenneman, Alicia Keys

Russell Brand, Charlie Haden

Bruce Willis, Sia

Bill Cosby, Matt Braunger

Emma Thompson, Michelle Felicetta, Purple Reign

Carla Bruni Sarkozy, Jack Hanna, Cold Hard Cash

Katie Couric, Dev Patel, Mr. Brownstone

Stephen Colbert, Kristen Stewart, Super Diamond

James Franco, Bruce McCall, The Allstarz

Nicole Kidman, Simon Baker, Kanye West

Reese Witherspoon, Harry Connick Jr.

Teri Hatcher, Ludacris

Denis Leary, John Mayer

Tom Arnold, Faith Hill

Jennifer Connelly, Anderson Cooper, The Duke Spirit

Amy Adams, Michael Sheen, Jamey Johnson

Keanu Reeves, Paula Abdul, Loudon Wainwright III

Sen. John McCain, Bon Iver

Meryl Streep, Jeff Altman

Adam Sandler

Tom Cruise, Fall Out Boy

Jennifer Aniston, Broken Social Scene

Will Smith, Of Montreal

Jerry Seinfeld, Leona Lewis

Dustin Hoffman, Todd Rundgren

Jay Thomas, Mickey Rourke, Darlene Love

Tracy Morgan, Matt Braunger

Kate Hudson, Glasvegas

Kevin James, Becky Quick, Erin McCarley

Ricky Gervais, Rose Byrne, Okkervil River

Kate Winslet, Marv Albert

Kiefer Sutherland, Wendy Liebman

Billy Crystal, Kara DioGuardi

Salma Hayek, Jimmie Walker

Clint Eastwood, Randy Rogers Band

Kyra Sedgwick, Gwen Ifill

Zach Braff, Arj Barker, The Airborne Toxic Event

Brian Williams, Ben Kweller

Evangeline Lilly, Seth Meyers, Andrew Bird